Identifying tandem Ankyrin repeats in protein structures
نویسندگان
چکیده
منابع مشابه
Tandem repeats in protein coding regions of primate genes.
Tandem repeats in GenBank primate nucleotide sequences annotated as protein coding regions are analyzed. It is found that only trinucleotide repeats show repeat enrichment well above the threshold of statistical significance. The statistics are improved by a simultaneous search for repeats on both the amino acid and nucleotide levels. The results of the analyses of natural sequences are interpr...
متن کاملGraph Centrality Analysis of Structural Ankyrin Repeats
In recent studies it has been shown that graph representation of protein structures is capable of capturing the 3-dimensional fold of the protein very well, thus providing a computationally efficient approach for protein structure analysis. Centrality measures are generally used to identify the relative importance of a node in the network. Here we demonstrate a novel application of centrality a...
متن کاملTandem Repeats in Prokaryotic Genomes
1 Department of Information Science, Graduate School of Science, Hirosaki University, 3 Bunkyo-cho, Hirosaki 036-8561, Japan 2 Department of Electronic and Information System Engineering, Faculty of Science and Technology, Hirosaki University, 3 Bunkyo-cho, Hirosaki 036-8561, Japan 3 Graduate School of Mathematics, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan 4 Protonic NanoMachine Pro...
متن کاملProtein repeats: structures, functions, and evolution.
Internal repetition within proteins has been a successful strategem on multiple separate occasions throughout evolution. Such protein repeats possess regular secondary structures and form multirepeat assemblies in three dimensions of diverse sizes and functions. In general, however, internal repetition affords a protein enhanced evolutionary prospects due to an enlargement of its available bind...
متن کاملSupporting Material Mechanical anisotropy of ankyrin repeats
When a transient pair of antiparallel helices is formed (Fig. 5A, middle panel), 11 contacts are formed, and also 11 contacts are formed when a transient loop-hairpin structure is created. Both processes shorten the polypeptide chain by 2 nm and the structures are inherently unstable and can easily open due to thermal fluctuations. If H2 of R16 had refolded to the stack, it would have formed on...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2014
ISSN: 1471-2105
DOI: 10.1186/s12859-014-0440-9